Genomics of Anaerobic Metabolism
We recently sequenced the genomes of anaerobic, alkane-degrading strains Desulfococcus oleovorans Hxd3 (Figure 1) and Desulfatibacillum alkenivorans AK-01 (Figure 2) in collaboration with DOE’s Joint Genome Institute. My current research focuses on investigating how these organisms “make a living” as sulfate reducers and in the context of alkane utilization.

Figure 1. Genome of Desulfococcus oleovorans Hxd3. Innermost ring: G+C skew; Second ring: G+C content; Third ring: Reverse CDS with COG designations; Fourth ring: Reverse strand; Fifth ring: Forward strand; Outermost ring: Forward CDS with COG designations.

Figure 2. Genome of Desulfatibacillum alkenivorans AK-01. Innermost ring: G+C skew; Second ring: G+C content; Third ring: Reverse CDS with COG designations; Fourth ring: Reverse strand; Fifth ring: Forward strand; Outermost ring: Forward CDS with COG designations.